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* MERS coronavirus has potential to spread globally, WHO

says

* U.N. health agency issues new guidance on pandemic risks

By Stephanie Nebehay

GENEVA, June 10 (Reuters) – The World Health Organisation on

Monday urged health workers around the world to be on the alert

for symptoms of the deadly Middle East respiratory syndrome

coronavirus (MERS), which has the potential to circle the globe

and cause a pandemic.

The United Nations agency, which issued new, long-awaited

guidance to countries on influenza pandemics, said the world was

also in the same “alert phase” for two human strains of bird flu

– H5N1, which emerged a decade ago, and H7N9, first detected in

China in March.

“We are trying to find out as much as we can and we are

concerned about these (three) viruses,” Andrew Harper, WHO

special adviser for health security and environment, told a news

briefing on its new scale for pandemic risk.

The interim guidance, to be finalised later this year,

incorporates lessons from the 2009/2010 pandemic of H1N1 swine

flu, which caused an estimated 200,000 deaths, roughly in line

with annual seasonal flu.

Having been adjusted to include the notion of severity when

assessing risk, the new scale has just four phases against six

previously and is intended to give countries more flexibility in

judging local risks.

“International concern about these infections is high,

because it is possible for this virus to move around the world.

There have been now several examples where the virus has moved

from one country to another through travellers,” the WHO said of

MERS, which causes coughing, fever and pneumonia.

Travellers have carried the virus to Britain, France,

Germany and Italy. Infected people have also been found in

Jordan, Qatar, Tunisia and the United Arab Emirates.

“Consequently, all countries in the world need to ensure

that their healthcare workers are aware of the virus and the

disease it can cause and that, when unexplained cases of

pneumonia are identified, MERS-CoV should be considered.”

MERS-coronavirus, a distant relative of SARS that emerged in

Saudi Arabia last year, has been confirmed in 55 people

worldwide, killing 31 of them. Forty cases occurred in Saudi

Arabia, many in a hospital in the eastern province of al-Ahsa.

“The overall number of cases is limited but the virus causes

death in about 60 percent of patients,” the WHO said, reporting

on a week-long mission of international experts to Saudi Arabia

that ended on Sunday.

“So far, about 75 percent of the cases in the Kingdom of

Saudi Arabia have been in men and most have occurred in people

with one or more major chronic conditions.”

But the source of the MERS virus remained unknown, it said.

Clusters of cases have occurred in families and health

facilities, indicating a limited capacity to spread among people

in close contact with an infected person, it said.

All countries in the Middle East should urgently intensify

disease surveillance to detect any MERS infections, it said.

The WHO has not yet drawn up advice for travellers ahead of

the annual haj pilgrimage in October, which draws millions of

Muslims to Saudi Arabia.

(Reporting by Stephanie Nebehay; editing by Mike Collett-White)